3bqo

X-ray diffraction
2Å resolution

Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
Non-polymer only tetramer
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Telomeric repeat-binding factor 1 Chain: A
Molecule details ›
Chain: A
Length: 211 amino acids
Theoretical weight: 24.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54274 (Residues: 58-268; Coverage: 48%)
Gene names: PIN2, TERF1, TRBF1, TRF, TRF1
Structure domains: Telomere repeat-binding factor, dimerisation domain
TERF1-interacting nuclear factor 2 Chain: B
Molecule details ›
Chain: B
Length: 21 amino acids
Theoretical weight: 2.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BSI4 (Residues: 257-276; Coverage: 4%)
Gene names: TIN2, TINF2

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P6122
Unit cell:
a: 117.105Å b: 117.105Å c: 88.018Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.22 0.237
Expression system: Escherichia coli BL21(DE3)