3bgf

X-ray diffraction
3Å resolution

X-ray crystal structure of the SARS coronavirus spike receptor binding domain in complex with F26G19 Fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chains: A, S
Molecule details ›
Chains: A, S
Length: 193 amino acids
Theoretical weight: 21.86 KDa
UniProt:
  • Canonical: P59594 (Residues: 318-510; Coverage: 16%)
Gene names: 2, S
Structure domains: Alpha-Beta Plaits
Anti-colorectal carcinoma light chain Chains: C, L
Molecule details ›
Chains: C, L
Length: 212 amino acids
Theoretical weight: 23.46 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q7TS98 (Residues: 23-234; Coverage: 99%)
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chains: B, H
Molecule details ›
Chains: B, H
Length: 220 amino acids
Theoretical weight: 23.63 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q8CGS2 (Residues: 3-105, 106-121; Coverage: 98%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21212
Unit cell:
a: 183.688Å b: 73.365Å c: 110.782Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.234 0.286