X-ray diffraction
2.3Å resolution

Structure of Xanthine Oxidase with 2-hydroxy-6-methylpurine


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-160412 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Xanthine dehydrogenase/oxidase Chains: A, I
Molecule details ›
Chains: A, I
Length: 219 amino acids
Theoretical weight: 24.04 KDa
Source organism: Bos taurus
  • Canonical: P80457 (Residues: 1-219; Coverage: 16%)
Gene name: XDH
Sequence domains:
Structure domains:
Xanthine dehydrogenase/oxidase Chains: B, J
Xanthine dehydrogenase/oxidase Chains: C, K

Ligands and Environments

Cofactor: Ligand MTE 2 x MTE

Cofactor: Ligand FAD 2 x FAD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 133.187Å b: 73.794Å c: 146.498Å
α: 90° β: 98.87° γ: 90°
R R work R free
0.197 0.194 0.263