3b84

X-ray diffraction
1.74Å resolution

Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)

Released:
Source organism: Homo sapiens
Entry authors: Filippakopoulos P, Bullock A, Cooper C, Keates T, Salah E, Pilka E, Pike ACW, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomere zinc finger-associated protein Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10074 (Residues: 4-120; Coverage: 17%)
Gene names: HKR3, TZAP, ZBTB48, ZNF855
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX10.1
Spacegroup: P3121
Unit cell:
a: 50.375Å b: 50.375Å c: 86.093Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.186 0.216
Expression system: Escherichia coli