3b75

X-ray diffraction
2.3Å resolution

Crystal Structure of Glycated Human Haemoglobin

Released:
Source organism: Homo sapiens
Entry authors: Saraswathi NT, Syakhovich VE, Bokut SB, Moras D, Ruff M

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: A, C, E, G, S
Molecule details ›
Chains: A, C, E, G, S
Length: 141 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chains: B, D, F, H, T
Molecule details ›
Chains: B, D, F, H, T
Length: 146 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 237.987Å b: 59.267Å c: 137.024Å
α: 90° β: 125.36° γ: 90°
R-values:
R R work R free
0.249 0.244 0.331