3apx

X-ray diffraction
2.2Å resolution

Crystal structure of the A variant of human alpha1-acid glycoprotein and chlorpromazine complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-1-acid glycoprotein 2 Chain: A
Molecule details ›
Chain: A
Length: 190 amino acids
Theoretical weight: 22.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19652 (Residues: 19-201; Coverage: 100%)
Gene names: AGP2, ORM2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P212121
Unit cell:
a: 42.125Å b: 63.077Å c: 64.957Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.202 0.268
Expression system: Escherichia coli