3am9

X-ray diffraction
2.17Å resolution

Complex of bovine xanthine dehydrogenase and trihydroxy FYX-051

Released:
Source organism: Bos taurus
Primary publication:
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase.
J. Pharmacol. Exp. Ther. 336 95-103 (2011)
PMID: 20952484

Function and Biology Details

Structure analysis Details

Ligands and Environments


Cofactor: Ligand FAD 2 x FAD

Cofactor: Ligand MTE 2 x MTE

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: C2
Unit cell:
a: 168.916Å b: 124.722Å c: 146.195Å
α: 90° β: 91.04° γ: 90°
R-values:
R R work R free
0.177 0.174 0.243