PDBe 3al4

X-ray diffraction
2.87Å resolution

Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemagglutinin Chains: A, C, E, G, I, K
Molecule details ›
Chains: A, C, E, G, I, K
Length: 333 amino acids
Theoretical weight: 36.99 KDa
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: C3W5S1 (Residues: 18-344; Coverage: 58%)
Gene name: HA
Structure domains:
Hemagglutinin Chains: B, D, F, H, J, L
Molecule details ›
Chains: B, D, F, H, J, L
Length: 181 amino acids
Theoretical weight: 20.76 KDa
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: C3W5S1 (Residues: 345-520; Coverage: 31%)
Gene name: HA
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P1
Unit cell:
a: 66.02Å b: 115.19Å c: 114.985Å
α: 62.31° β: 77.94° γ: 81.05°
R-values:
R R work R free
0.247 0.246 0.27
Expression system: Spodoptera frugiperda