X-ray diffraction
2.33Å resolution

alpha-L-fucosidase complexed with inhibitor, F10-2C-O


Function and Biology Details

Reaction catalysed:
An alpha-L-fucoside + H(2)O = L-fucose + an alcohol
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Alpha-L-fucosidase, putative Chains: A, B
Molecule details ›
Chains: A, B
Length: 455 amino acids
Theoretical weight: 53.1 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
  • Canonical: Q9WYE2 (Residues: 1-449; Coverage: 100%)
Gene name: TM_0306
Sequence domains: Alpha-L-fucosidase
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: R32
Unit cell:
a: 180.075Å b: 180.075Å c: 169.61Å
α: 90° β: 90° γ: 120°
R R work R free
0.167 0.165 0.212
Expression system: Escherichia coli