2zsw

X-ray diffraction
2.8Å resolution

Crystal structure of H-2Kb in complex with the Q600Y variant of JHMV epitope S598

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135047 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class I histocompatibility antigen, K-B alpha chain Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 278 amino acids
Theoretical weight: 32.07 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01901 (Residues: 22-299; Coverage: 80%)
Gene names: H2-K, H2-K1
Sequence domains:
Structure domains:
Beta-2-microglobulin Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 99 amino acids
Theoretical weight: 11.7 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01887 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Spike protein S1 Chains: M, N, O, P
Molecule details ›
Chains: M, N, O, P
Length: 8 amino acids
Theoretical weight: 982 Da
Source organism: Murine hepatitis virus strain JHM
Expression system: Not provided
UniProt:
  • Canonical: P11225 (Residues: 457-464; Coverage: 1%)
Gene names: 3, S

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 66.711Å b: 90.147Å c: 91.969Å
α: 81.11° β: 70.58° γ: 68.25°
R-values:
R R work R free
0.214 0.212 0.253
Expression systems:
  • Escherichia coli
  • Not provided