X-ray diffraction
1.61Å resolution

Function and Biology Details

Reaction catalysed:
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Uricase Chain: A
Molecule details ›
Chain: A
Length: 302 amino acids
Theoretical weight: 34.18 KDa
Source organism: Aspergillus flavus
Expression system: Saccharomyces cerevisiae
  • Canonical: Q00511 (Residues: 2-302; Coverage: 100%)
Gene names: uaZ, uox
Sequence domains: Uricase
Structure domains: Urate Oxidase;

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: I222
Unit cell:
a: 80.172Å b: 96.227Å c: 105.408Å
α: 90° β: 90° γ: 90°
R R work R free
0.174 0.173 0.19
Expression system: Saccharomyces cerevisiae