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Crystal structure of ribosomal protein L11 methyltransferase from Thermus thermophilus in complex with S-adenosyl-L-methionine

X-ray diffraction
2.3Å resolution
PDB entry 2zbp coloured by chain, front view.
PDB entry 2zbp coloured by chain, side view.
PDB entry 2zbp coloured by chain, top view.
Source organism: Thermus thermophilus
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Ribosomal protein L11 methyltransferase
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Multimeric state: monomeric
Accessible surface area: 12695.21 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-183019
Assembly 2
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Assembly Name: Ribosomal protein L11 methyltransferase
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Multimeric state: homo dimer
Accessible surface area: 22967.27 Å2
Buried surface area: 2427.16 Å2
Dissociation area: 1,213.58 Å2
Dissociation energy (ΔGdiss): 9.24 kcal/mol
Dissociation entropy (TΔSdiss): 13.65 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-183020

Macromolecules

Ribosomal protein L11 methyltransferase
Chain: A
Length: 254 amino acids
Theoretical weight: 27.66 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q84BQ9 (Residues: 1-254; Coverage: 100%)
Gene names: TTHA0656, prmA
Pfam: Ribosomal protein L11 methyltransferase (PrmA)
InterPro:
CATH:
Ribosomal protein L11 methyltransferase in PDB entry 2zbp, assembly 1, front view.
Ribosomal protein L11 methyltransferase in PDB entry 2zbp, assembly 1, side view.
Ribosomal protein L11 methyltransferase in PDB entry 2zbp, assembly 1, top view.
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