2z9a

X-ray diffraction
2.5Å resolution

Crystal Structure of Human Saposin C Dimer in Open Conformation

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Saposin-C Chains: A, B
Molecule details ›
Chains: A, B
Length: 88 amino acids
Theoretical weight: 10.15 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P07602 (Residues: 311-389; Coverage: 16%)
Gene names: GLBA, PSAP, SAP1
Sequence domains:
Structure domains: Saposin-like

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P41212
Unit cell:
a: 48.99Å b: 48.99Å c: 155.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.239 0.271
Expression system: Komagataella pastoris