Structure analysis

Crystal structure of AR LBD with SHP peptide NR Box 2

X-ray diffraction
2.6Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: A
Length: 248 amino acids
Theoretical weight: 28.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10275 (Residues: 672-919; Coverage: 27%)
Gene names: AR, DHTR, NR3C4
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
CATH: Retinoid X Receptor
SCOP: Nuclear receptor ligand-binding domain

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Chain: B
Length: 10 amino acids
Theoretical weight: 1.16 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15466 (Residues: 115-124; Coverage: 4%)
Gene names: NR0B2, SHP

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