Structure analysis

Crystal structure of Keap1 complexed with Prothymosin alpha

X-ray diffraction
2Å resolution
Source organism: Mus musculus
Assembly composition:
Non-polymer only dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: Non-polymer only dimer
Accessible surface area: 12100 Å2
Buried surface area: 1800 Å2
Dissociation area: 450 Å2
Dissociation energy (ΔGdiss): 1 kcal/mol
Dissociation entropy (TΔSdiss): 7 kcal/mol
Interface energy (ΔGint): -60 kcal/mol
Symmetry number: 1

Macromolecules

Chain: A
Length: 318 amino acids
Theoretical weight: 35.01 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Z2X8 (Residues: 308-624; Coverage: 51%)
Gene names: Inrf2, Keap1, Kiaa0132
Pfam: Kelch motif
InterPro:
CATH: Kelch-type beta propeller
SCOP: Kelch motif

Search similar proteins

Chain: B
Length: 16 amino acids
Theoretical weight: 1.79 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P26350 (Residues: 39-54; Coverage: 14%)
Gene name: Ptma

Search similar proteins