› › Structure analysis

The crystal structure of human Atg4B- LC3(1-124) complex

X-ray diffraction
1.9Å resolution
PDB 2z0e coloured by chain and viewed from the front.
PDB 2z0e coloured by chain and viewed from the side.
PDB 2z0e coloured by chain and viewed from the top.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer

Binding statistics and energies are not available for this assembly

Macromolecules

Cysteine protease ATG4B
Chain: A
Length: 357 amino acids
Theoretical weight: 40.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9Y4P1 (Residues: 1-353; Coverage: 90%)
Gene names: APG4B, ATG4B, AUTL1, KIAA0943
Pfam: Peptidase family C54
InterPro:
SCOP: Autophagin-like
PDB 2z0e contains 1 copy of Cysteine protease ATG4B in assembly 1. This protein is highlighted and viewed from the front.
PDB 2z0e contains 1 copy of Cysteine protease ATG4B in assembly 1. This protein is highlighted and viewed from the side.
PDB 2z0e contains 1 copy of Cysteine protease ATG4B in assembly 1. This protein is highlighted and viewed from the top.
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Microtubule-associated proteins 1A/1B light chain 3B
Chain: B
Length: 129 amino acids
Theoretical weight: 14.93 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q62625 (Residues: 1-124; Coverage: 87%)
Gene names: Map1alc3, Map1lc3, Map1lc3b
Pfam: Autophagy protein Atg8 ubiquitin like
InterPro:
CATH: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
SCOP: GABARAP-like
PDB 2z0e contains 1 copy of Microtubule-associated proteins 1A/1B light chain 3B in assembly 1. This protein is highlighted and viewed from the front.
PDB 2z0e contains 1 copy of Microtubule-associated proteins 1A/1B light chain 3B in assembly 1. This protein is highlighted and viewed from the side.
PDB 2z0e contains 1 copy of Microtubule-associated proteins 1A/1B light chain 3B in assembly 1. This protein is highlighted and viewed from the top.
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