› 2yxs

X-ray diffraction
2.13Å resolution

Crystal Structure of N-terminal domain of human galectin-8 with D-lactose

Released:
DOI: 10.2210/pdb2yxs/pdb
PDB entry 2yxs coloured by chain, front view.
PDB entry 2yxs coloured by chain, side view.
PDB entry 2yxs coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kishishita S, Nishino A, Murayama K, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-8 Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 18.1 KDa
Source organism: Homo sapiens
Expression system: Cell-free protein synthesis
UniProt:
  • Canonical: O00214 (Residues: 1-151; Coverage: 48%)
Gene name: LGALS8
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL
Carbohydrate polymer
No bound ligands
1 modified residue:
Ligand MSE 1 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P212121
Unit cell:
a: 45.913Å b: 50.551Å c: 69.336Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 0.234
Expression system: Cell-free protein synthesis

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