EC 1.14.11.27: [Histone H3]-dimethyl-L-lysine(36) demethylase
Reaction catalysed:
(1a) a [histone H3]-N(6),N(6)-dimethyl-L-lysine(36) + 2-oxoglutarate + O(2) = a [histone H3]-N(6)-methyl-L-lysine(36) + succinate + formaldehyde + CO(2)
Systematic name:
[Histone H3]-N(6),N(6)-dimethyl-L-lysine(36),2-oxoglutarate:oxygen oxidoreductase
Alternative Name(s):
- H3-K36-specific demethylase
- Histone demethylase
- Histone-lysine (H3-K36) demethylase
- JHDM1A
- JmjC domain-containing histone demethylase 1A
- Protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase
- [Histone-H3]-lysine-36 demethylase
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence family
Protein family (Pfam)
InterPro annotationsStructure domains
CATH domains
1.20.58.1360
Class:
Mainly Alpha
Architecture:
Up-down Bundle
Topology:
Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homology:
Methane Monooxygenase Hydroxylase; Chain G, domain 1
Occurring in:
