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Crystal Structure of D-isomer specific 2-hydroxyacid dehydrogenase from Lactobacillus delbrueckii ssp. bulgaricus: NAD complexed form

X-ray diffraction
2.75Å resolution
PDB 2yq5 coloured by chain and viewed from the front.
PDB 2yq5 coloured by chain and viewed from the side.
PDB 2yq5 coloured by chain and viewed from the top.
Source organism: Lactobacillus delbrueckii subsp. bulgaricus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Multimeric state: homo tetramer

Binding statistics and energies are not available for this assembly

Macromolecules

D-isomer specific 2-hydroxyacid dehydrogenase
Chains: A, B, C, D
Length: 343 amino acids
Theoretical weight: 38.03 KDa
Source organism: Lactobacillus delbrueckii subsp. bulgaricus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q1GAA2 (Residues: 1-333; Coverage: 100%)
Gene name: Ldb1010
Pfam:
InterPro:
CATH: NAD(P)-binding Rossmann-like Domain
PDB 2yq5 contains 4 copies of D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE in assembly 1. This protein is highlighted and viewed from the front.
PDB 2yq5 contains 4 copies of D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE in assembly 1. This protein is highlighted and viewed from the side.
PDB 2yq5 contains 4 copies of D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE in assembly 1. This protein is highlighted and viewed from the top.
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