X-ray diffraction
2.75Å resolution

Crystal Structure of D-isomer specific 2-hydroxyacid dehydrogenase from Lactobacillus delbrueckii ssp. bulgaricus: NAD complexed form


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
D-isomer specific 2-hydroxyacid dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 343 amino acids
Theoretical weight: 38.03 KDa
Source organism: Lactobacillus delbrueckii subsp. bulgaricus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q1GAA2 (Residues: 1-333; Coverage: 100%)
Gene name: Ldb1010
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 92.718Å b: 110.012Å c: 147.736Å
α: 90° β: 90° γ: 90°
R R work R free
0.191 0.188 0.259
Expression system: Escherichia coli BL21(DE3)