2ypg

X-ray diffraction
2.85Å resolution

Haemagglutinin of 1968 Human H3N2 Virus in Complex with Human Receptor Analogue LSTc

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (8 distinct):
Hemagglutinin HA1 chain Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 328 amino acids
Theoretical weight: 36.07 KDa
Source organism: Influenza A virus (A/X-31(H3N2))
UniProt:
  • Canonical: P03437 (Residues: 17-344; Coverage: 60%)
Gene name: HA
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Hemagglutinin HA2 chain Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 175 amino acids
Theoretical weight: 20.21 KDa
Source organism: Influenza A virus (A/X-31(H3N2))
UniProt:
  • Canonical: P03437 (Residues: 346-520; Coverage: 32%)
Gene name: HA
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUL
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BGC, GAL, SIA
Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer : NEW Components: NAG, BMA
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P41
Unit cell:
a: 160.767Å b: 160.767Å c: 177.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.177 0.19