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Oligomeric assembly of actin bound to MRTF-A

Source organisms:
Biochemical function: cytoskeletal motor activator activity
Biological process: mesenchyme migration
Cellular component: skeletal muscle myofibril

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF02755
Domain description: RPEL repeat
Occurring in:
  1. Myocardin-related transcription factor A
The deposited structure of PDB entry 2yje contains 3 copies of Pfam domain PF02755 (RPEL repeat) in Myocardin-related transcription factor A. Showing 3 copies in chain D [auth M] (some of the copies are out of the observed residue ranges!).

PF00022
Domain description: Actin
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 2yje contains 3 copies of Pfam domain PF00022 (Actin) in Actin, alpha skeletal muscle. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR004000
Domain description: Actin family
Occurring in:
  1. Actin, alpha skeletal muscle
IPR004018
Domain description: RPEL repeat
Occurring in:
  1. Myocardin-related transcription factor A
IPR004001
Domain description: Actin, conserved site
Occurring in:
  1. Actin, alpha skeletal muscle
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. Actin, alpha skeletal muscle
IPR020902
Domain description: Actin/actin-like conserved site
Occurring in:
  1. Actin, alpha skeletal muscle
IPR043451
Domain description: Myocardin-like
Occurring in:
  1. Myocardin-related transcription factor A

Structure domains

CATH CATH domains
3.30.420.40
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nucleotidyltransferase; domain 5
Homology: Nucleotidyltransferase; domain 5
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 2yje contains 6 copies of CATH domain 3.30.420.40 (Nucleotidyltransferase; domain 5) in Actin, alpha skeletal muscle. Showing 2 copies in chain B.
3.90.640.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Actin; Chain A, domain 4
Homology: Actin; Chain A, domain 4
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 2yje contains 3 copies of CATH domain 3.90.640.10 (Actin; Chain A, domain 4) in Actin, alpha skeletal muscle. Showing 1 copy in chain B.
6.10.140.2040
Class: Special
Architecture: Helix non-globular
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. Myocardin-related transcription factor A
The deposited structure of PDB entry 2yje contains 1 copy of CATH domain 6.10.140.2040 (Helix Hairpins) in Myocardin-related transcription factor A. Showing 1 copy in chain D [auth M].

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