2yd9

X-ray diffraction
2.6Å resolution

Crystal structure of the N-terminal Ig1-3 module of Human Receptor Protein Tyrosine Phosphatase Sigma

Released:

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Receptor-type tyrosine-protein phosphatase S Chain: A
Molecule details ›
Chain: A
Length: 304 amino acids
Theoretical weight: 33.26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q13332 (Residues: 30-334; Coverage: 15%)
  • Best match: Q13332-6 (Residues: 30-321)
Gene name: PTPRS
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: I222
Unit cell:
a: 71.699Å b: 90.043Å c: 143.283Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.247 0.289
Expression system: Homo sapiens