2y92

X-ray diffraction
3.01Å resolution

Crystal structure of MAL adaptor protein

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toll/interleukin-1 receptor domain-containing adapter protein Chain: A
Molecule details ›
Chain: A
Length: 145 amino acids
Theoretical weight: 15.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P58753 (Residues: 79-221; Coverage: 65%)
Gene names: MAL, TIRAP
Sequence domains: TIR domain
Structure domains: Toll/interleukin-1 receptor homology (TIR) domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P43212
Unit cell:
a: 88.146Å b: 88.146Å c: 78.793Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.23 0.251
Expression system: Escherichia coli BL21(DE3)