PDBe 2y3j

X-ray diffraction
1.99Å resolution

Structure of segment AIIGLM from the amyloid-beta peptide (Ab, residues 30-35)

Released:
Source organism: Homo sapiens
Primary publication:
Molecular basis for amyloid-beta polymorphism.
Proc. Natl. Acad. Sci. U.S.A. 108 16938-43 (2011)
PMID: 21949245

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
P3(40) Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 6 amino acids
Theoretical weight: 617 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 701-706; Coverage: 1%)
Gene names: A4, AD1, APP

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P1
Unit cell:
a: 9.56Å b: 15.64Å c: 45.23Å
α: 89.87° β: 90.02° γ: 89.91°
R-values:
R R work R free
0.225 0.222 0.267
Expression system: Not provided