2xxc

X-ray diffraction
1.67Å resolution

Crystal structure of a camelid VHH raised against the HIV-1 capsid protein C-terminal domain.

Released:
Source organism: Vicugna pacos
Entry authors: Igonet S, Vaney MC, Bartonova V, Helma J, Rothbauer U, Leonhardt H, Stura E, Krausslich H-G, Rey FA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CAMELID VHH 9 Chain: B
Molecule details ›
Chain: B
Length: 121 amino acids
Theoretical weight: 13.21 KDa
Source organism: Vicugna pacos
Expression system: Escherichia coli BL21(DE3)
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P41212
Unit cell:
a: 80.208Å b: 80.208Å c: 52.686Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.21
Expression system: Escherichia coli BL21(DE3)