PDBe 2xwr

X-ray diffraction
1.68Å resolution

Crystal structure of the DNA-binding domain of human p53 with extended N terminus

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chains: A, B
Molecule details ›
Chains: A, B
Length: 205 amino acids
Theoretical weight: 23.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P04637 (Residues: 89-293)
Gene names: P53, TP53

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 51.5Å b: 68.45Å c: 58.89Å
α: 90° β: 99.46° γ: 90°
R-values:
R R work R free
0.175 0.173 0.209
Expression system: Escherichia coli