2xtt

X-ray diffraction
0.93Å resolution

Bovine trypsin in complex with evolutionary enhanced Schistocerca gregaria protease inhibitor 1 (SGPI-1-P02)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protease inhibitor SGPI-1 Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 3.93 KDa
Source organism: Schistocerca gregaria
Expression system: Not provided
UniProt:
  • Canonical: O46162 (Residues: 20-54; Coverage: 48%)
Cationic trypsin Chain: B
Molecule details ›
Chain: B
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 36.91Å b: 63.61Å c: 43.87Å
α: 90° β: 93.85° γ: 90°
R-values:
R R work R free
0.117 not available 0.14
Expression system: Not provided