2xrp

Electron Microscopy
8.2Å resolution

Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the 8-Angstrom Cryo-EM Map of Doublecortin- Stabilised Microtubules

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Tubulin beta-2B chain Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 445 amino acids
Theoretical weight: 49.91 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q6B856 (Residues: 1-445; Coverage: 100%)
Gene name: TUBB2B
Sequence domains:
Tubulin alpha-1D chain Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 452 amino acids
Theoretical weight: 50.24 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q2HJ86 (Residues: 1-452; Coverage: 100%)
Gene name: TUBA1D
Sequence domains:
Neuronal migration protein doublecortin Chain: I
Molecule details ›
Chain: I
Length: 95 amino acids
Theoretical weight: 11.03 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O43602 (Residues: 46-140; Coverage: 26%)
Gene names: DBCN, DCX, LISX
Sequence domains: Doublecortin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 8.2Å
Relevant EMDB volumes: EMD-1788
Expression system: Spodoptera frugiperda