2xra

X-ray diffraction
2.3Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 228 amino acids
Theoretical weight: 25.72 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04578 (Residues: 543-582, 625-662; Coverage: 10%)
Gene name: env
HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 223 amino acids
Theoretical weight: 23.61 KDa
Source organism: Homo sapiens
Structure domains: Immunoglobulins
HK20, HUMAN MONOCLONAL ANTIBODY LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.63 KDa
Source organism: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 75.947Å b: 62.71Å c: 76.61Å
α: 90° β: 97.7° γ: 90°
R-values:
R R work R free
0.239 0.237 0.279
Expression system: Escherichia coli BL21(DE3)