Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assemblies composition:
Assembly name:
Complement factor H and Complement C3d fragment (preferred)
PDBe Complex ID:
PDB-CPX-133856 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement C3d fragment
Molecule details ›
Chains: A, B
Length: 294 amino acids
Theoretical weight: 32.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: A-macroglobulin TED domain
Structure domains: Glycosyltransferase
Length: 294 amino acids
Theoretical weight: 32.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P01024 (Residues: 996-1287; Coverage: 18%)
Sequence domains: A-macroglobulin TED domain
Structure domains: Glycosyltransferase
Complement factor H
Molecule details ›
Chain: C
Length: 133 amino acids
Theoretical weight: 14.98 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
Length: 133 amino acids
Theoretical weight: 14.98 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
- Canonical: P08603 (Residues: 1103-1231; Coverage: 11%)
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-1
Spacegroup:
P61
Expression systems:
- Escherichia coli BL21(DE3)
- Komagataella pastoris
