Single particle analysis of Kir2.1NC_4 in negative stain


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Inward rectifier potassium channel 2 Chains: I, J, K, L
Molecule details ›
Chains: I, J, K, L
Length: 309 amino acids
Theoretical weight: 34.98 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
  • Canonical: P35561 (Residues: 1-67, 189-428; Coverage: 72%)
Gene names: Irk1, Kcnj2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Experimental Method: Electron Microscopy, X-ray solution scattering
Resolution: 17.2Å
Relevant EMDB volumes: EMD-1764
Expression system: Escherichia coli BL21