2xkj

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA topoisomerase 4 subunit A; DNA topoisomerase 4 subunit B Chain: E
Molecule details ›
Chain: E
Length: 767 amino acids
Theoretical weight: 86.09 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B0V9T6 (Residues: 370-627; Coverage: 41%)
  • Canonical: B0VP98 (Residues: 1-503; Coverage: 68%)
Gene names: ABAYE0126, ABSDF0217, parC, parE
Sequence domains:
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2
Unit cell:
a: 163.389Å b: 74.433Å c: 80.211Å
α: 90° β: 107.96° γ: 90°
R-values:
R R work R free
0.163 0.161 0.213
Expression system: Escherichia coli BL21(DE3)