› › Structure analysis

Structure of Nek2 bound to aminopyrazine compound 17

X-ray diffraction
2.1Å resolution
PDB entry 2xk4 coloured by chain, front view.
PDB entry 2xk4 coloured by chain, side view.
PDB entry 2xk4 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Serine/threonine-protein kinase Nek2
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 13710.26 Å2
Buried surface area: 721.27 Å2
Dissociation area: 26.17 Å2
Dissociation energy (ΔGdiss): 3.84 kcal/mol
Dissociation entropy (TΔSdiss): -0.84 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-156438

Macromolecules

Serine/threonine-protein kinase Nek2
Chain: A
Length: 279 amino acids
Theoretical weight: 32.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P51955 (Residues: 1-271; Coverage: 61%)
Gene names: NEK2, NEK2A, NLK1
Pfam: Protein kinase domain
InterPro:
CATH:
Serine/threonine-protein kinase Nek2 in PDB entry 2xk4, assembly 1, front view.
Serine/threonine-protein kinase Nek2 in PDB entry 2xk4, assembly 1, side view.
Serine/threonine-protein kinase Nek2 in PDB entry 2xk4, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links