X-ray diffraction
1.95Å resolution

Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Methylmalonyl-CoA mutase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 762 amino acids
Theoretical weight: 84.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P22033 (Residues: 12-750; Coverage: 99%)
Gene names: MMUT, MUT
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand B12 1 x B12

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2221
Unit cell:
a: 59.36Å b: 137.72Å c: 198.4Å
α: 90° β: 90° γ: 90°
R R work R free
0.16 0.158 0.199
Expression system: Escherichia coli BL21(DE3)