2xgy

X-ray diffraction
1.8Å resolution

Complex of Rabbit Endogenous Lentivirus (RELIK)Capsid with Cyclophilin A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RELIK CAPSID N-TERMINAL DOMAIN Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 16.51 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli BL21(DE3)
Structure domains: Human Immunodeficiency Virus Type 1 Capsid Protein
Peptidyl-prolyl cis-trans isomerase A Chain: B
Molecule details ›
Chain: B
Length: 173 amino acids
Theoretical weight: 18.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62937 (Residues: 1-165; Coverage: 100%)
Gene names: CYPA, PPIA
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P61
Unit cell:
a: 117.158Å b: 117.158Å c: 49.655Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.157 0.156 0.187
Expression system: Escherichia coli BL21(DE3)