Structure analysis

Structure of HSP90 with small molecule inhibitor bound

X-ray diffraction
1.98Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: homo dimer
Accessible surface area: 18700 Å2
Buried surface area: 2700 Å2
Dissociation area: 750 Å2
Dissociation energy (ΔGdiss): 3 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): -10 kcal/mol
Symmetry number: 2

Macromolecules

Search similar proteins