PDBe 2x99

X-ray diffraction
2.3Å resolution

Thioredoxin glutathione reductase from Schistosoma mansoni in complex with NADPH


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glutaredoxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 598 amino acids
Theoretical weight: 65.06 KDa
Source organism: Schistosoma mansoni
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q962Y6 (Residues: 1-598; Coverage: 100%)
Gene name: TGR
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C2
Unit cell:
a: 141.502Å b: 102.61Å c: 59.938Å
α: 90° β: 112.82° γ: 90°
R R work R free
0.192 0.19 0.231
Expression system: Escherichia coli BL21(DE3)