2x6l

X-ray diffraction
2.6Å resolution

X-ray Structure of Macrophage Inflammatory Protein-1 beta

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo decamer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 4 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 69 amino acids
Theoretical weight: 7.82 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P13236 (Residues: 24-92; Coverage: 100%)
Gene names: CCL4, LAG1, MIP1B, SCYA4
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 59.811Å b: 87.892Å c: 186.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.186 0.26
Expression system: Not provided