2x55

X-ray diffraction
1.85Å resolution

Yersinia Pestis Plasminogen Activator Pla (Native)

Released:

Function and Biology Details

Reaction catalysed:
Converts human Glu-plasminogen to plasmin by cleaving the 560-Arg-|-Val-561 peptide bond that is also hydrolyzed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coagulase/fibrinolysin Chain: A
Molecule details ›
Chain: A
Length: 293 amino acids
Theoretical weight: 32.71 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17811 (Residues: 21-312; Coverage: 100%)
Gene names: YPPCP1.07, YP_pPCP08, pla
Sequence domains: Omptin family
Structure domains: OMPT-like

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P6522
Unit cell:
a: 140.341Å b: 140.341Å c: 130.426Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.196 0.209
Expression system: Escherichia coli BL21(DE3)