X-ray diffraction
1.4Å resolution

Crystal Structure of Arg r 1 in complex with histamine

Source organism: Argas reflexus
Entry authors: Paesen GC, Siebold C, Syme N, Harlos K, Graham SC, Hilger C, Homans SW, Hentges F, Stuart DI

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Allergen Arg r 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 144 amino acids
Theoretical weight: 15.52 KDa
Source organism: Argas reflexus
Expression system: Escherichia coli
  • Canonical: Q5GQ85 (Residues: 17-159; Coverage: 100%)
Sequence domains: Tick histamine binding protein
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2
Unit cell:
a: 107.147Å b: 61.817Å c: 63.871Å
α: 90° β: 105.14° γ: 90°
R R work R free
0.133 0.13 0.183
Expression system: Escherichia coli