› 2x2z

X-ray diffraction
2Å resolution

Crystal structure AMA1 from Toxoplasma gondii

Released:
DOI: 10.2210/pdb2x2z/pdb
PDB entry 2x2z coloured by chain, front view.
PDB entry 2x2z coloured by chain, side view.
PDB entry 2x2z coloured by chain, top view.
Source organism: Toxoplasma gondii
Primary publication:
Structural characterization of apical membrane antigen 1 (AMA1) from Toxoplasma gondii.
Crawford J, Tonkin ML, Grujic O, Boulanger MJ
J Biol Chem 285 15644-15652 (2010)
PMID: 20304917

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110352 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apical membrane antigen 1, soluble form Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 456 amino acids
Theoretical weight: 50.49 KDa
Source organism: Toxoplasma gondii
Expression system: Trichoplusia ni
UniProt:
  • Canonical: B6KAM0 (Residues: 64-519; Coverage: 88%)
Gene names: AMA1, TGVEG_255260
Sequence domains: Apical membrane antigen 1
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NAG 4 x NAG
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P1
Unit cell:
a: 66.15Å b: 76.07Å c: 88.25Å
α: 72.19° β: 71.44° γ: 72.9°
R-values:
R R work R free
0.183 0.18 0.248
Expression system: Trichoplusia ni

Quick links

Citations

4 review citations

The moving junction of apicomplexan parasites: a key structure for invasion.
Besteiro et al. (2011)
3 more

7 mentions without citation

The apicomplexan glideosome and adhesins - Structures and function.
Boucher et al. (2015)
6 more