X-ray diffraction
2.8Å resolution

Crystal structure of Importin13 - RanGTP complex


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GTP-binding nuclear protein GSP1/CNR1 Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 19.77 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21
  • Canonical: P32835 (Residues: 8-179; Coverage: 79%)
Gene names: CNR1, CST17, GSP1, L8003.19, YLR293C
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Importin-13 Chain: B
Molecule details ›
Chain: B
Length: 963 amino acids
Theoretical weight: 109.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: O94829 (Residues: 1-963; Coverage: 100%)
Gene names: IPO13, KIAA0724, RANBP13
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 99.93Å b: 99.93Å c: 276.84Å
α: 90° β: 90° γ: 120°
R R work R free
0.236 0.236 0.268
Expression system: Escherichia coli BL21