X-ray diffraction
3Å resolution

Crystal structure of the complete EphA2 ectodomain

Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Ephrin type-A receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 545 amino acids
Theoretical weight: 60.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
  • Canonical: P29317 (Residues: 11-534; Coverage: 53%)
Gene names: ECK, EPHA2
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P1
Unit cell:
a: 41.92Å b: 44.65Å c: 93.42Å
α: 93.02° β: 98.22° γ: 112.12°
R R work R free
0.239 0.236 0.299
Expression system: Homo sapiens