PDBe 2x04

X-ray diffraction
1.49Å resolution

Crystal structure of the PABC-TNRC6C complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polyadenylate-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 80 amino acids
Theoretical weight: 8.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P11940 (Residues: 545-619; Coverage: 12%)
Gene names: PAB1, PABP1, PABPC1, PABPC2
Sequence domains: Poly-adenylate binding protein, unique domain
Structure domains: c-terminal domain of poly(a) binding protein
Trinucleotide repeat-containing gene 6C protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 18 amino acids
Theoretical weight: 2.09 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9HCJ0 (Residues: 1382-1399; Coverage: 1%)
Gene names: KIAA1582, TNRC6C

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 37.11Å b: 72.23Å c: 37.04Å
α: 90° β: 119.76° γ: 90°
R-values:
R R work R free
0.164 0.163 0.186
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided