X-ray diffraction
1.7Å resolution

Staphylococcus aureus complement subversion protein Sbi-IV in complex with complement fragment C3d revealing an alternative binding mode


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement C3d fragment Chain: A
Molecule details ›
Chain: A
Length: 310 amino acids
Theoretical weight: 34.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P01024 (Residues: 996-1303; Coverage: 19%)
Gene names: C3, CPAMD1
Structure domains: Glycosyltransferase
Molecule details ›
Chain: Q
Length: 80 amino acids
Theoretical weight: 9.26 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
Structure domains: Sbi, C3 binding domain IV

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 53.43Å b: 81.01Å c: 87.83Å
α: 90° β: 90° γ: 90°
R R work R free
0.174 0.172 0.205
Expression system: Escherichia coli BL21(DE3)