Structure analysis

Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I

X-ray diffraction
1.8Å resolution
Source organism: Clostridium perfringens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 15300 Å2
Buried surface area: 1300 Å2
Dissociation area: 50 Å2
Dissociation energy (ΔGdiss): 3 kcal/mol
Dissociation entropy (TΔSdiss): 1 kcal/mol
Interface energy (ΔGint): -131 kcal/mol
Symmetry number: 1

Macromolecules

Chain: A
Length: 370 amino acids
Theoretical weight: 42.6 KDa
Source organism: Clostridium perfringens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0TV31 (Residues: 29-398; Coverage: 100%)
Gene names: CPF_0042, cpa, plc
Pfam:
InterPro:
CATH:

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