X-ray diffraction
1.8Å resolution

Crystal structure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron in complex with a novel iminosugar fucosidase inhibitor


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Alpha-L-fucosidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 443 amino acids
Theoretical weight: 51.33 KDa
Source organism: Bacteroides thetaiotaomicron VPI-5482
Expression system: Escherichia coli BL21
  • Canonical: Q8A3I4 (Residues: 31-473; Coverage: 97%)
Gene name: BT_2970
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Unit cell:
a: 104.83Å b: 85.16Å c: 121.285Å
α: 90° β: 108.73° γ: 90°
R R work R free
0.209 0.207 0.245
Expression system: Escherichia coli BL21