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structure of influenza H2 avian hemagglutinin with avian receptor

X-ray diffraction
2.4Å resolution
PDB entry 2wr2 coloured by chain, front view.
PDB entry 2wr2 coloured by chain, side view.
PDB entry 2wr2 coloured by chain, top view.
Source organism: unidentified influenza virus
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Hemagglutinin-esterase-fusion glycoprotein
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Multimeric state: homo trimer
Accessible surface area: 59372.95 Å2
Buried surface area: 16679.52 Å2
Dissociation area: 7,240.58 Å2
Dissociation energy (ΔGdiss): 50.69 kcal/mol
Dissociation entropy (TΔSdiss): 32.25 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-112060

Macromolecules

Hemagglutinin-esterase-fusion glycoprotein
Chains: A, B, C
Length: 509 amino acids
Theoretical weight: 57.59 KDa
Source organism: unidentified influenza virus
Expression system: Not provided
UniProt:
  • Canonical: D0VWP8 (Residues: 1-509; Coverage: 100%)
Gene name: HE
Pfam: Haemagglutinin
InterPro:
CATH:
Hemagglutinin-esterase-fusion glycoprotein in PDB entry 2wr2, assembly 1, front view.
Hemagglutinin-esterase-fusion glycoprotein in PDB entry 2wr2, assembly 1, side view.
Hemagglutinin-esterase-fusion glycoprotein in PDB entry 2wr2, assembly 1, top view.
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