2wqi

X-ray diffraction
1.7Å resolution

Crystal structure of the human p73 tetramerization domain

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor protein p73 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 51 amino acids
Theoretical weight: 6.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15350 (Residues: 350-399; Coverage: 8%)
Gene names: P73, TP73
Structure domains: p53-like tetramerisation domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: R3
Unit cell:
a: 76.11Å b: 76.11Å c: 79.63Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.209 0.254
Expression system: Escherichia coli